Eh it depends, some python packages do things like pull data samples from my experience and it can be quite a mess detangling the package to give PyInstaller everything it needs to bundle stuff up. It also takes a lot of additional configuration for a lot of packages.

As much as I hate how containers are often misused, this is one of the reasons people obsess over them from my experience. The ability to bundle all your crap regardless of how many layers of package management idiosyncrasies your application ultimately woul have to deal with pretty much transparently.