I ditched my desktop once "plug in a single USB-C cable and get dual 4k monitors + peripherals all ready to go" became a thing. I love the flexibility of a laptop combined with a dedicated workstation setup.
It matters in the sense that my 2015 Macbook Pro required multiple cables to unplug/replug in at my desk which seems like a small thing but significantly reduced the convenience factor for me.
Plus I can now dock either my Lenovo or my MacBook with the same multi-monitor dock making it even more versatile. I don't game or do anything more intensive than web development so I recognize it wouldn't work as well for everyone.