DRM used to work; I installed Chrome in Lutris and managed to get Amazon Prime working, though Chrome was very buggy. Netflix sort of works in Firefox (needs an addon to play 1080p video, no idea about 4k).
Microsoft Office (at least, a version that's kept up to date) doesn't work in Wine. I find ONLYOFFICE to be a very competent replacement, though.
I've also used Cassowary to configure a Windows 10 VM + Remote Desktop Apps, which allow for Windows programs to appear native in the Linux launcher while secretly launching the VM and starting an RDP session for that application alone. It's a bit fiddly to set up, but it works if you rarely ever use Office.
As a last resort, you could do what Microsoft did with Windows 11 when Wordpad got removed: install Microsoft Office Online as a web application (requires Chromium/WebKit browser to be installed since Mozilla decided PWAs aren't important to desktop users).
If you don't care much about privacy risks, you could also skip the Linux crap and install ChromeOS Flex. It's probably the most user-friendly Linux desktop out there, and DRM should work out of the box.
Or just use reactos' Wordpad. Get their ISO, use 7zip to uncompress it, and search inside for a bigass CAB file which is hundred of MB's in size. Extract that with 7zip again under a "ros" folder and you'll have WordPad.exe, Calc and lots of goodies for free (as in freedom) in your Windows machine.
Microsoft Office (at least, a version that's kept up to date) doesn't work in Wine. I find ONLYOFFICE to be a very competent replacement, though.
I've also used Cassowary to configure a Windows 10 VM + Remote Desktop Apps, which allow for Windows programs to appear native in the Linux launcher while secretly launching the VM and starting an RDP session for that application alone. It's a bit fiddly to set up, but it works if you rarely ever use Office.
As a last resort, you could do what Microsoft did with Windows 11 when Wordpad got removed: install Microsoft Office Online as a web application (requires Chromium/WebKit browser to be installed since Mozilla decided PWAs aren't important to desktop users).
If you don't care much about privacy risks, you could also skip the Linux crap and install ChromeOS Flex. It's probably the most user-friendly Linux desktop out there, and DRM should work out of the box.